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Rheumatoid Arthritis Treatment: From Medications To Surgery

By John Ugoshowa

It is believed that rheumatoid does not have any known cure and at best, early and aggressive treatment of rheumatoid may significantly help in managing the disease as well as improve pain control and alleviate stiffness and fatigue. Rheumatoid treatment may be undertaken by using Rituxan which is a drug that is thought to be showing promising results and this drug, which is also known as Mabthera or Rituximab works by targeting B-cells and it may also be used to pave the way for other smart treatments to rheumatoid arthritis. Rheumatoid treatment has so far only focused on treating the symptoms or modifying the disease process though lack of specificity may cause healthy cells to die along with the diseased cells.

Pain Is The Major Reason Why People Seek Treatment

It is believed that a majority of people suffering from rheumatoid rank pain as the main reason for seeking professional help and for rheumatoid treatment. Non-steroid anti-inflammatory drugs (NSAIDs) are used for rheumatoid treatment because these agents can block prostaglandins which are the substances that dilate blood vessels and result in inflammation as well as pain and of the dozens of NSAIDs; the most common ones are over-the-counter NSAIDs including aspirin, ibuprofen, and naproxen.

There are also prescription NSAIDs including ibuprofen and naproxen and flurbiprofen. According to studies conducted on rheumatoid treatment, there are indications that optimal times for taking an NSAID is after the evening meal and once more when one awakens and this is mainly due to the fact that the rheumatoid symptoms increase gradually at night and peak when one awakens. Taking NSAIDs accompanied


by food may be instrumental in greatly reducing stomach discomfort even though there may be a slowing down in the pain-relieving effort.

Besides taking NSAIDs for rheumatoid treatment one may also use a device called the Prosorba column which removes the inflammatory antibodies from the blood of the patient and this rheumatoid treatment works by first removing the blood from the body of the patient using a catheter and then passing the blood through a column that is no bigger than a coffee mug. The column is coated with protein A that helps to bind the antibodies and the blood is then returned to the patient and the procedure lasts for about 2 ½ hours and is performed once every week for twelve weeks. According to information available such therapies can slow or even half the progression of rheumatoid in one third to half of the patients getting this kind of rheumatoid treatment.

Article Source: http://www.articlemap.com

John Ugoshowa. You are welcome to use this article on your website or in your ezinesas long as you have a link back to www.quickregister.net For more information on see the section of Quickregister.net Free Search Engine Submission Service at: www.quickregister.net/infowizards/SUB/Arthritis_115_1.html





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Safety and Effectiveness of Adalimumab in Patients Diagnosed With Rheumatoid Arthritis
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   Biological: adalimumab (Humira)<br/><b>Sponsor</b>:   Abbott<br/><b>Active, not recruiting</b> - verified February 2010
A Study on the Prevalence of the Anti-MCV Anti-body in an Irish Rheumatoid Arthritis (RA) Population and the Impact of Biomarker Status on the Management of Irish Patients With Early RA
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   Other: This is a non-drug study. No treatment is mandated by the protocol. Routine blood draws (as per normal clinical care) will be taken through the study.<br/><b>Sponsors</b>:   Abbott;   Clinical Trial End-Point (CTEP) Ltd;   JSS Medical Research Inc.<br/><b>Not yet recruiting</b> - verified March 2010
Cost Utility Analyses of Adalimumab Treatment in Patients With Rheumatoid Arthritis (RA)
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   <br/><b>Sponsors</b>:   Abbott;   Institute of Political Economical & Social Researches, Greece<br/><b>Active, not recruiting</b> - verified February 2010
Effectiveness of Adalimumab on Extraarticular Manifestation in Patients With Active Rheumatoid Arthritis
<b>Conditions</b>:   Active Rheumatoid Arthritis;   Osteoporoses<br/><b>Intervention</b>:   <br/><b>Sponsors</b>:   Abbott;   Centre of Biostatistics and Analyses, Faculty of Medicine, Masaryk University Brno, Czech Republic<br/><b>Recruiting</b> - verified February 2010
The Relation Between Dedicated Extremity MRI Synovitis and Structural Deterioration Radiographic in Patients With Rheumatoid Arthritis in Clinical Remission. Preliminary Study
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   Other: MRI<br/><b>Sponsor</b>:   Centre Hospitalier Universitaire de Nice<br/><b>Not yet recruiting</b> - verified January 2010
Efficacy of Oncoxin Plus Viusid in the Treatment of Rheumatoid Arthritis
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Interventions</b>:   Dietary Supplement: Oncoxin + Viusid;   Dietary Supplement: Placebo<br/><b>Sponsor</b>:   Catalysis SL<br/><b>Recruiting</b> - verified November 2009
Monitoring Epstein-Barr Virus (EBV) Load in Rheumatoid Arthritis Patients Treated With New Immunosuppressive Drugs
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   Biological: Venous blood sample<br/><b>Sponsor</b>:   Assistance Publique Hopitaux De Marseille<br/><b>Recruiting</b> - verified October 2009
A Study Of PF-04171327 In The Treatment Of The Signs And Symptoms Of Rheumatoid Arthritis
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Interventions</b>:   Drug: PF-04171327 10 mg;   Other: Prednisone Placebo;   Drug: PF-04171327 25 mg;   Other: Prednisone Placebo;   Drug: Prednisone 5 mg;   Other: Placebo for PF-04171327;   Other: Placebo;   Other: Placebo for PF-04171327<br/><b>Sponsor</b>:   Pfizer<br/><b>Recruiting</b> - verified March 2010
Targeting Synovitis in Early Rheumatoid Arthritis
<b>Conditions</b>:   Rheumatoid Arthritis;   Polyarthritis<br/><b>Interventions</b>:   Other: Musculoskeletal Ultrasound;   Other: 28 Joint Disease Activity Score<br/><b>Sponsors</b>:   NHS Greater Glasgow and Clyde;   University of Glasgow;   Chief Scientist Office of the Scottish Government;   Wyeth;   Translational Medicine Research Collaboration<br/><b>Recruiting</b> - verified September 2009
Living Well With Rheumatoid Arthritis
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Interventions</b>:   Behavioral: Self-Help Group;   Other: Education (Control) Group<br/><b>Sponsors</b>:   Brigham and Women's Hospital;   Bristol-Myers Squibb<br/><b>Recruiting</b> - verified September 2009
A Study to Evaluate the RNA Signature of Rheumatoid Arthritis From Synovium and Whole Blood
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   <br/><b>Sponsors</b>:   Imperial College London;   Merck<br/><b>Recruiting</b> - verified February 2010
Ultrasonography as a Biomarker in Early Rheumatoid Arthritis
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   <br/><b>Sponsors</b>:   Imperial College London;   Medical Research Council<br/><b>Recruiting</b> - verified February 2010
Evaluation of EULAR-RAID Score in Rheumatoid Arthritis Patients
<b>Condition</b>:   Active Rheumatoid Arthritis<br/><b>Intervention</b>:   Drug: Etanercept<br/><b>Sponsor</b>:   Wyeth<br/><b>Recruiting</b> - verified July 2009
A Study Comparing CRx-102 Plus Disease-Modifying Anti-Rheumatic Drug (DMARD) Therapy to Placebo Plus DMARD Therapy in Rheumatoid Arthritis
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Interventions</b>:   Other: CRx-102 plus DMARD therapy;   Other: Placebo plus DMARD therapy<br/><b>Sponsor</b>:   CombinatoRx<br/><b>Completed</b> - verified September 2008
Effects of Tranilast on Pharmacokinetics of Methotrexate (MTX) in Patients With Rheumatoid Arthritis (RA)
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Interventions</b>:   Drug: Tranilast;   Drug: Placebo comparator<br/><b>Sponsors</b>:   Imperial College London;   Nuon Therapeutics, Inc.<br/><b>Withdrawn</b> - verified July 2009
RESTART C0168Z05 Rheumatoid Arthritis Study
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   Biological: Infliximab<br/><b>Sponsors</b>:   Centocor Ortho Biotech Services, L.L.C.;   Schering-Plough<br/><b>Active, not recruiting</b> - verified January 2010
Humira in Rheumatoid Arthritis - Do Bone Erosions Heal?
<b>Conditions</b>:   Rheumatoid Arthritis;   Arthritis;   Joint Diseases<br/><b>Intervention</b>:   Drug: Adalimumab (Humira)<br/><b>Sponsors</b>:   Hvidovre University Hospital;   Abbott<br/><b>Completed</b> - verified June 2008
Rosuvastatin in Rheumatoid Arthritis (RORA)
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Interventions</b>:   Drug: rosuvastatin;   Drug: placebo<br/><b>Sponsor</b>:   University of Dundee<br/><b>Completed</b> - verified May 2008
Rheumatoid Arthritis (RA) Moderate to Low Disease Activity Study
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Interventions</b>:   Drug: Certolizumab pegol;   Other: Placebo<br/><b>Sponsor</b>:   UCB, Inc.<br/><b>Recruiting</b> - verified February 2010
Study Evaluating Single Doses of SBI-087 in Subjects With Rheumatoid Arthritis
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   Drug: SBI-087<br/><b>Sponsors</b>:   Wyeth;   Trubion Pharmaceuticals<br/><b>Active, not recruiting</b> - verified July 2009

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