|
|
Additional
Resources
|
|
Arthritis Information And Help Is Only A Click Away
By Paul Heath
Keeping up to date with the latest arthritis information is vital for anyone that lives daily with the pain and suffering arthritis can cause. Research continues to make progress mainly in Read more...
|
|
|
|
Arthritis
Degenerative Arthritis – A Bird’s Eye Look At The Disease
By John Ugoshowa
The definition of degenerative says that this is also known as osteoarthritis. This is normally caused by ever so gradual damage and loss of cartilage situated at the joints. With the cartilage gone, the affected joint becomes misshapen in the end and disappears totally. There are more than one hundred different types of known to us and among all these types, degenerative is the most common of all.
What Happens When Degenerative Sets In?
As explained a little earlier, degenerative causes total damage to the cartilage that cushions the movement between any two given joints. Once the cartilage is gone, the movement is effected with bone grating on bone which explains the extreme pain that this disease is well known for. With the cartilage gone, the constant rubbing by bone against bone causes localized inflammation, which culminates in the two bones fusing together with the help of a new bone formation (a protrusion normally known as a spur).
One of the earliest signs of degenerative is the change in shape of the smallest (top most) joint of the fingers. The cartilage there being the tiniest is among the first (easiest) prey to the devastating effects of the disease. The hand affected by osteoarthritis is quite deformed by the formation of such fusion on different fingers.
The other joints that this type of attacks are those of the feet (toes
in particular), the spinal chord and the joints which bear large amounts of weight such as the knees, the hip joints and so on. The osteoarthritis is classified into two main categories, (i) when the causes of the disease is not well known; it is named primary osteoarthritis and (ii) when the causes of the disease are known, it is named secondary osteoarthritis.
Causes of the primary osteoarthritis – doctors are of the opinion that age is the main cause of this disease. Aging saps the cartilage of water content while depleting its protein content resulting into its gradual degeneration. The cartilage gets frayed with age and movement, when at last (over long years) you will find that there is no more cartilage to lose or damage any longer. The bone inflammation prompts new bone formation resulting into ugly “bumps” called spurs which totally deform the joint.
There have been a number of instances where primary osteoarthritis has been hereditary, spreading over two or three generations. The secondary osteoarthritis is mostly caused by being overweight, gout, hormone disorders, trauma to joints and diabetes to name a few of the biggest culprits. John Ugoshowa. You are welcome to use this article on your website or in your ezinesas long as you have a link back to www.quickregister.net For more information on see the section of Quickregister.net Free Search Engine Submission Service at: www.quickregister.net/infowizards/SUB/Arthritis_115_1.html
We strive to provide only quality information, so
if
there is a specific topic related to arthritis
that you would
like us to cover, please contact us at any time.
And again, thank you to those contributing daily to
our Arthritis
Website, especially
regarding "joint pain in hands".
Discounted
Arthritis Online Auction
If you can't find the
Arthritis information you are looking for please
try our Google
Search
Time to DMARD (Disease-Modifying Anti-Rheumatic Drug) Treatment and Actual Work Limitation of Patients With Rheumatoid Arthritis in Turkey
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: <br/><b>Sponsor</b>: Abbott<br/><b>Recruiting</b> - verified June 2010
Hydroxychloroquine to Improve Insulin Sensitivity in Rheumatoid Arthritis
<b>Conditions</b>: Rheumatoid Arthritis; Insulin Resistance<br/><b>Intervention</b>: Drug: Hydroxychloroquine<br/><b>Sponsors</b>: Brigham and Women's Hospital; National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)<br/><b>Not yet recruiting</b> - verified May 2010
Iyengar Yoga for Young People With Rheumatoid Arthritis
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: Behavioral: Iyengar Yoga<br/><b>Sponsor</b>: University of California, Los Angeles<br/><b>Recruiting</b> - verified March 2010
Safety and Effectiveness of Adalimumab in Patients Diagnosed With Rheumatoid Arthritis
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: Biological: adalimumab (Humira)<br/><b>Sponsor</b>: Abbott<br/><b>Completed</b> - verified August 2010
Cost Utility Analyses of Adalimumab Treatment in Patients With Rheumatoid Arthritis (RA)
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: <br/><b>Sponsors</b>: Abbott; Institute of Political Economical & Social Researches, Greece<br/><b>Active, not recruiting</b> - verified July 2010
Effectiveness of Adalimumab on Extraarticular Manifestation in Patients With Active Rheumatoid Arthritis
<b>Conditions</b>: Active Rheumatoid Arthritis; Osteoporoses<br/><b>Intervention</b>: <br/><b>Sponsors</b>: Abbott; Centre of Biostatistics and Analyses, Faculty of Medicine, Masaryk University Brno, Czech Republic<br/><b>Recruiting</b> - verified June 2010
Study of Human Leukocyte Antigen (HLA) Polymorphisms in Patients With Rheumatoid Arthritis
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: Biological: Collect of 10 ml of peripheric blood for DNA extraction<br/><b>Sponsor</b>: Centre Hospitalier Universitaire de Fort-de-France<br/><b>Enrolling by invitation</b> - verified April 2010
Efficacy of Oncoxin Plus Viusid in the Treatment of Rheumatoid Arthritis
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Interventions</b>: Dietary Supplement: Oncoxin + Viusid; Dietary Supplement: Placebo<br/><b>Sponsor</b>: Catalysis SL<br/><b>Recruiting</b> - verified November 2009
Monitoring Epstein-Barr Virus (EBV) Load in Rheumatoid Arthritis Patients Treated With New Immunosuppressive Drugs
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: Biological: Venous blood sample<br/><b>Sponsor</b>: Assistance Publique Hopitaux De Marseille<br/><b>Recruiting</b> - verified October 2009
Targeting Synovitis in Early Rheumatoid Arthritis
<b>Conditions</b>: Rheumatoid Arthritis; Polyarthritis<br/><b>Interventions</b>: Other: Musculoskeletal Ultrasound; Other: 28 Joint Disease Activity Score<br/><b>Sponsors</b>: NHS Greater Glasgow and Clyde; University of Glasgow; Chief Scientist Office of the Scottish Government; Wyeth; Translational Medicine Research Collaboration<br/><b>Recruiting</b> - verified September 2009
Living Well With Rheumatoid Arthritis
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Interventions</b>: Behavioral: Self-Help Group; Other: Education (Control) Group<br/><b>Sponsors</b>: Brigham and Women's Hospital; Bristol-Myers Squibb<br/><b>Recruiting</b> - verified May 2010
A Study to Evaluate the RNA Signature of Rheumatoid Arthritis From Synovium and Whole Blood
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: <br/><b>Sponsors</b>: Imperial College London; Merck<br/><b>Recruiting</b> - verified February 2010
Ultrasonography as a Biomarker in Early Rheumatoid Arthritis
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: <br/><b>Sponsors</b>: Imperial College London; Medical Research Council<br/><b>Recruiting</b> - verified February 2010
Evaluation of EULAR-RAID Score in Rheumatoid Arthritis Patients
<b>Condition</b>: Active Rheumatoid Arthritis<br/><b>Intervention</b>: Drug: Etanercept<br/><b>Sponsor</b>: Wyeth<br/><b>Recruiting</b> - verified July 2009
A Study Comparing CRx-102 Plus Disease-Modifying Anti-Rheumatic Drug (DMARD) Therapy to Placebo Plus DMARD Therapy in Rheumatoid Arthritis
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Interventions</b>: Other: CRx-102 plus DMARD therapy; Other: Placebo plus DMARD therapy<br/><b>Sponsor</b>: CombinatoRx<br/><b>Completed</b> - verified September 2008
Effects of Tranilast on Pharmacokinetics of Methotrexate (MTX) in Patients With Rheumatoid Arthritis (RA)
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Interventions</b>: Drug: Tranilast; Drug: Placebo comparator<br/><b>Sponsors</b>: Imperial College London; Nuon Therapeutics, Inc.<br/><b>Withdrawn</b> - verified July 2009
RESTART C0168Z05 Rheumatoid Arthritis Study
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: Biological: Infliximab<br/><b>Sponsors</b>: Centocor Ortho Biotech Services, L.L.C.; Schering-Plough<br/><b>Completed</b> - verified July 2010
Humira in Rheumatoid Arthritis - Do Bone Erosions Heal?
<b>Conditions</b>: Rheumatoid Arthritis; Arthritis; Joint Diseases<br/><b>Intervention</b>: Drug: Adalimumab (Humira)<br/><b>Sponsors</b>: Hvidovre University Hospital; Abbott<br/><b>Completed</b> - verified June 2008
Rheumatoid Arthritis (RA) Moderate to Low Disease Activity Study
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Interventions</b>: Drug: Certolizumab pegol; Other: Placebo<br/><b>Sponsor</b>: UCB, Inc.<br/><b>Active, not recruiting</b> - verified June 2010
Study Evaluating Single Doses of SBI-087 in Subjects With Rheumatoid Arthritis
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: Drug: SBI-087<br/><b>Sponsors</b>: Wyeth; Trubion Pharmaceuticals<br/><b>Active, not recruiting</b> - verified July 2009
|
|
