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What Are Your Choices For Arthritis Relief?

By John Ugoshowa
Arthritis is almost synonymous with pain. The person who has been affected by the disease will be able to tell how difficult it is living with it. There are many things that one can do to have a Read more...

Arthritis


Arthritis, Gout – Rich Man’s Knee Pain

By Darry J.Oswald

There are many causes of knee pain, such as overuse, obesity, or injury. However, there are two main causes of knee pain, they are and gout. If you are one of the millions of Americans suffering with knee pain or pain in the knee you may benefit from the many studies done on this subject. The three basic types of that may cause hip and knee pain: osteoarthritis and inflammatory (most commonly rheumatoid arthritis), and traumatic arthritis.

Autoimmune disorders such as rheumatoid or systemic lupus erythematosus can cause knee pain. In children, chronic knee pain may be the first sign of rheumatoid or simply "growing pains". Knee pain may result from trauma, overuse, internal derangement, osteoarthritis, or inflammatory arthritis. The differential diagnoses include inflammatory arthritis, bursitis or tendonitis, anterior knee pain and internal derangement.

Gout the another main reason for knee pains. Gout is a condition that causes sudden and severe attacks of pain, redness and swelling of joints. Gout is a condition has been well known for many centuries. Most often it affects a single joint in one episode, often the big toe. About 9 out of 10 affected individuals affected by gout are men over the age of 40. The peak age of attacks is 75 years, but it can occur in young individuals on rare occasions. Over one millions Americans have a gout attack each year.

Gout is due to accumulations of uric acid within the fluid of your joints. Uric acid is a waste product of many foods that we eat. In order to properly digest food, and rid our body of waste, we produce substances such as uric acid to transport waste material. Ultimately, uric acid is excreted via the kidneys in urine. However, when the transportation of uric acid is impaired, and uric acid accumulates in the blood


stream, the condition called gout may result. The impairment of uric acid excretion is often due to a hereditary problem, but can also have other causes.

When the uric acid level becomes too high for an individual, painful attacks of gouty arthritis, or joint pain, can result. Other symptoms can include kidney stones, and, ultimately, kidney failure. It is interesting to note that the relationship between uric acid levels in the blood stream and gout is unclear. Some individuals with gout have normal or near normal blood levels of uric acid; other individuals have very high blood levels of uric acid with no symptoms of gout. It appears to be entirely dependent on the individual.

Some individuals have a hereditary condition making them more susceptible to gout; other risk factors also contribute to having a gouty attack. Among these are obesity and sudden weight gain, abnormal kidney function, excessive intake of alcohol (especially "binge" drinking), and certain types of cancer. Some medications, such as thiazide diuretics to control blood pressure, and foods that are rich in purines can lead to attacks. Purine-rich foods include organ meats (e.g. liver, kidney), herring, anchovies, and to an extent, all meat products.

Article Source: http://www.articlemap.com

Many things can slow down your active lifestyle, but Knee Pains can definitely bring it to a stop. Come Find out More about Knee Pain at KneePain.eabout.info





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Safety and Effectiveness of Adalimumab in Patients Diagnosed With Rheumatoid Arthritis
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   Biological: adalimumab (Humira)<br/><b>Sponsor</b>:   Abbott<br/><b>Active, not recruiting</b> - verified February 2010
A Study on the Prevalence of the Anti-MCV Anti-body in an Irish Rheumatoid Arthritis (RA) Population and the Impact of Biomarker Status on the Management of Irish Patients With Early RA
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   Other: This is a non-drug study. No treatment is mandated by the protocol. Routine blood draws (as per normal clinical care) will be taken through the study.<br/><b>Sponsors</b>:   Abbott;   Clinical Trial End-Point (CTEP) Ltd;   JSS Medical Research Inc.<br/><b>Not yet recruiting</b> - verified March 2010
Cost Utility Analyses of Adalimumab Treatment in Patients With Rheumatoid Arthritis (RA)
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   <br/><b>Sponsors</b>:   Abbott;   Institute of Political Economical & Social Researches, Greece<br/><b>Active, not recruiting</b> - verified February 2010
Effectiveness of Adalimumab on Extraarticular Manifestation in Patients With Active Rheumatoid Arthritis
<b>Conditions</b>:   Active Rheumatoid Arthritis;   Osteoporoses<br/><b>Intervention</b>:   <br/><b>Sponsors</b>:   Abbott;   Centre of Biostatistics and Analyses, Faculty of Medicine, Masaryk University Brno, Czech Republic<br/><b>Recruiting</b> - verified February 2010
The Relation Between Dedicated Extremity MRI Synovitis and Structural Deterioration Radiographic in Patients With Rheumatoid Arthritis in Clinical Remission. Preliminary Study
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   Other: MRI<br/><b>Sponsor</b>:   Centre Hospitalier Universitaire de Nice<br/><b>Not yet recruiting</b> - verified January 2010
Efficacy of Oncoxin Plus Viusid in the Treatment of Rheumatoid Arthritis
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Interventions</b>:   Dietary Supplement: Oncoxin + Viusid;   Dietary Supplement: Placebo<br/><b>Sponsor</b>:   Catalysis SL<br/><b>Recruiting</b> - verified November 2009
Monitoring Epstein-Barr Virus (EBV) Load in Rheumatoid Arthritis Patients Treated With New Immunosuppressive Drugs
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   Biological: Venous blood sample<br/><b>Sponsor</b>:   Assistance Publique Hopitaux De Marseille<br/><b>Recruiting</b> - verified October 2009
A Study Of PF-04171327 In The Treatment Of The Signs And Symptoms Of Rheumatoid Arthritis
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Interventions</b>:   Drug: PF-04171327 10 mg;   Other: Prednisone Placebo;   Drug: PF-04171327 25 mg;   Other: Prednisone Placebo;   Drug: Prednisone 5 mg;   Other: Placebo for PF-04171327;   Other: Placebo;   Other: Placebo for PF-04171327<br/><b>Sponsor</b>:   Pfizer<br/><b>Recruiting</b> - verified March 2010
Targeting Synovitis in Early Rheumatoid Arthritis
<b>Conditions</b>:   Rheumatoid Arthritis;   Polyarthritis<br/><b>Interventions</b>:   Other: Musculoskeletal Ultrasound;   Other: 28 Joint Disease Activity Score<br/><b>Sponsors</b>:   NHS Greater Glasgow and Clyde;   University of Glasgow;   Chief Scientist Office of the Scottish Government;   Wyeth;   Translational Medicine Research Collaboration<br/><b>Recruiting</b> - verified September 2009
Living Well With Rheumatoid Arthritis
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Interventions</b>:   Behavioral: Self-Help Group;   Other: Education (Control) Group<br/><b>Sponsors</b>:   Brigham and Women's Hospital;   Bristol-Myers Squibb<br/><b>Recruiting</b> - verified September 2009
A Study to Evaluate the RNA Signature of Rheumatoid Arthritis From Synovium and Whole Blood
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   <br/><b>Sponsors</b>:   Imperial College London;   Merck<br/><b>Recruiting</b> - verified February 2010
Ultrasonography as a Biomarker in Early Rheumatoid Arthritis
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   <br/><b>Sponsors</b>:   Imperial College London;   Medical Research Council<br/><b>Recruiting</b> - verified February 2010
Evaluation of EULAR-RAID Score in Rheumatoid Arthritis Patients
<b>Condition</b>:   Active Rheumatoid Arthritis<br/><b>Intervention</b>:   Drug: Etanercept<br/><b>Sponsor</b>:   Wyeth<br/><b>Recruiting</b> - verified July 2009
A Study Comparing CRx-102 Plus Disease-Modifying Anti-Rheumatic Drug (DMARD) Therapy to Placebo Plus DMARD Therapy in Rheumatoid Arthritis
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Interventions</b>:   Other: CRx-102 plus DMARD therapy;   Other: Placebo plus DMARD therapy<br/><b>Sponsor</b>:   CombinatoRx<br/><b>Completed</b> - verified September 2008
Effects of Tranilast on Pharmacokinetics of Methotrexate (MTX) in Patients With Rheumatoid Arthritis (RA)
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Interventions</b>:   Drug: Tranilast;   Drug: Placebo comparator<br/><b>Sponsors</b>:   Imperial College London;   Nuon Therapeutics, Inc.<br/><b>Withdrawn</b> - verified July 2009
RESTART C0168Z05 Rheumatoid Arthritis Study
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   Biological: Infliximab<br/><b>Sponsors</b>:   Centocor Ortho Biotech Services, L.L.C.;   Schering-Plough<br/><b>Active, not recruiting</b> - verified January 2010
Humira in Rheumatoid Arthritis - Do Bone Erosions Heal?
<b>Conditions</b>:   Rheumatoid Arthritis;   Arthritis;   Joint Diseases<br/><b>Intervention</b>:   Drug: Adalimumab (Humira)<br/><b>Sponsors</b>:   Hvidovre University Hospital;   Abbott<br/><b>Completed</b> - verified June 2008
Rosuvastatin in Rheumatoid Arthritis (RORA)
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Interventions</b>:   Drug: rosuvastatin;   Drug: placebo<br/><b>Sponsor</b>:   University of Dundee<br/><b>Completed</b> - verified May 2008
Rheumatoid Arthritis (RA) Moderate to Low Disease Activity Study
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Interventions</b>:   Drug: Certolizumab pegol;   Other: Placebo<br/><b>Sponsor</b>:   UCB, Inc.<br/><b>Recruiting</b> - verified February 2010
Study Evaluating Single Doses of SBI-087 in Subjects With Rheumatoid Arthritis
<b>Condition</b>:   Rheumatoid Arthritis<br/><b>Intervention</b>:   Drug: SBI-087<br/><b>Sponsors</b>:   Wyeth;   Trubion Pharmaceuticals<br/><b>Active, not recruiting</b> - verified July 2009

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