Arthritis
Arthritis Treatment - Some Alternatives to Consider
By May Owen
Arthritis Treatments
At the present time there is no cure for psoriatic arthritis. Your health carer attempts to control the inflammation in your joints affected by in order to reduce and hopefully prevent joint pain and the associated. This is usually accomplished with a number of different treatments. Usually the treatments preferred are medications and in severe cases surgery may be required.
(No particular order is given to the treatments listed below)
Arthritis Treatments No. 1
Corticosteroids. If you have mild psoriatic arthritis, your health carer may suggest corticosteroids to control occasional joint pain. These can be taken orally, or can be injected directly into aching joints.
Corticosteroid injections provide almost immediate relief and improve the condition often for a period of months. But because injected steroids can cause damage, their use is usually restricted.
Arthritis Treatments No. 2
Medications commonly used to treat psoriatic include:
Nonsteroidal anti-inflammatory drugs (NSAIDs). Drugs such as aspirin and ibuprofen (Advil, Motrin, others) may help control pain, swelling and morning stiffness. Prescription NSAIDs provide higher potencies than do over-the-counter drugs. But all NSAIDs can irritate your stomach and intestine, and long-term use can lead to ulcers and gastrointestinal bleeding.
Other potential side effects include damage to your kidneys, fluid retention and heart failure. In addition, NSAIDs may worsen
skin problems. Still, these medications may be a good option for people with minor joint pain and stiffness.
Arthritis Treatments No. 3
Immunosuppressant medications. These drugs act to suppress the immune system, which normally protects the body from harmful organisms. In the case of psoriatic however, healthy tissue is damaged by the bodies natural defence mechanisms and suppressing this automatic response halts the damage caused by psoriatic arthritis. Some widely used immunosuppressants include cyclosporine (Sandimmune, Neoral), azathioprine (Imuran) and leflunomide (Arava).
These agents can have potentially dangerous side effects and usually are used in only the most severe cases of psoriatic arthritis. All such drugs can lead to anaemia and an increased risk of serious infection. And many of them can cause liver and kidney problems.
Arthritis Treatments No. 4
Disease-modifying antirheumatic drugs (DMARDs). Rather than just reducing pain and inflammation, this class of drugs helps limit the amount of joint damage that occurs in psoriatic arthritis. These agents act quite slowly and the effects may not be prevalent for weeks or perhaps even months. These are often used in conjunction with pain relivers to reduce discomfort during the initial phase of the treatment. Some examples of a DMARD Treatments are hydroxychloroquine (Plaquenil), methotrexate and sulfasalazine (Azulfidine).
Arthritis Treatments No. 5 - Surgery
Although surgery is rarely performed for arthritis, your health carer may suggest this course of action for some severe cases, usually after other treatments have failed to be effective.
There are various surgical procedures to ease pain and restore mobility. Because these operations pose some risks, be sure you thoroughly discuss your options with your doctor before taking this course of action.
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Time to DMARD (Disease-Modifying Anti-Rheumatic Drug) Treatment and Actual Work Limitation of Patients With Rheumatoid Arthritis in Turkey
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: <br/><b>Sponsor</b>: Abbott<br/><b>Recruiting</b> - verified June 2010
Hydroxychloroquine to Improve Insulin Sensitivity in Rheumatoid Arthritis
<b>Conditions</b>: Rheumatoid Arthritis; Insulin Resistance<br/><b>Intervention</b>: Drug: Hydroxychloroquine<br/><b>Sponsors</b>: Brigham and Women's Hospital; National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)<br/><b>Not yet recruiting</b> - verified May 2010
Iyengar Yoga for Young People With Rheumatoid Arthritis
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: Behavioral: Iyengar Yoga<br/><b>Sponsor</b>: University of California, Los Angeles<br/><b>Recruiting</b> - verified March 2010
Safety and Effectiveness of Adalimumab in Patients Diagnosed With Rheumatoid Arthritis
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: Biological: adalimumab (Humira)<br/><b>Sponsor</b>: Abbott<br/><b>Active, not recruiting</b> - verified February 2010
Cost Utility Analyses of Adalimumab Treatment in Patients With Rheumatoid Arthritis (RA)
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: <br/><b>Sponsors</b>: Abbott; Institute of Political Economical & Social Researches, Greece<br/><b>Active, not recruiting</b> - verified July 2010
Effectiveness of Adalimumab on Extraarticular Manifestation in Patients With Active Rheumatoid Arthritis
<b>Conditions</b>: Active Rheumatoid Arthritis; Osteoporoses<br/><b>Intervention</b>: <br/><b>Sponsors</b>: Abbott; Centre of Biostatistics and Analyses, Faculty of Medicine, Masaryk University Brno, Czech Republic<br/><b>Recruiting</b> - verified June 2010
Study of Human Leukocyte Antigen (HLA) Polymorphisms in Patients With Rheumatoid Arthritis
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: Biological: Collect of 10 ml of peripheric blood for DNA extraction<br/><b>Sponsor</b>: Centre Hospitalier Universitaire de Fort-de-France<br/><b>Enrolling by invitation</b> - verified April 2010
Efficacy of Oncoxin Plus Viusid in the Treatment of Rheumatoid Arthritis
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Interventions</b>: Dietary Supplement: Oncoxin + Viusid; Dietary Supplement: Placebo<br/><b>Sponsor</b>: Catalysis SL<br/><b>Recruiting</b> - verified November 2009
Monitoring Epstein-Barr Virus (EBV) Load in Rheumatoid Arthritis Patients Treated With New Immunosuppressive Drugs
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: Biological: Venous blood sample<br/><b>Sponsor</b>: Assistance Publique Hopitaux De Marseille<br/><b>Recruiting</b> - verified October 2009
Targeting Synovitis in Early Rheumatoid Arthritis
<b>Conditions</b>: Rheumatoid Arthritis; Polyarthritis<br/><b>Interventions</b>: Other: Musculoskeletal Ultrasound; Other: 28 Joint Disease Activity Score<br/><b>Sponsors</b>: NHS Greater Glasgow and Clyde; University of Glasgow; Chief Scientist Office of the Scottish Government; Wyeth; Translational Medicine Research Collaboration<br/><b>Recruiting</b> - verified September 2009
Living Well With Rheumatoid Arthritis
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Interventions</b>: Behavioral: Self-Help Group; Other: Education (Control) Group<br/><b>Sponsors</b>: Brigham and Women's Hospital; Bristol-Myers Squibb<br/><b>Recruiting</b> - verified May 2010
A Study to Evaluate the RNA Signature of Rheumatoid Arthritis From Synovium and Whole Blood
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: <br/><b>Sponsors</b>: Imperial College London; Merck<br/><b>Recruiting</b> - verified February 2010
Ultrasonography as a Biomarker in Early Rheumatoid Arthritis
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: <br/><b>Sponsors</b>: Imperial College London; Medical Research Council<br/><b>Recruiting</b> - verified February 2010
Evaluation of EULAR-RAID Score in Rheumatoid Arthritis Patients
<b>Condition</b>: Active Rheumatoid Arthritis<br/><b>Intervention</b>: Drug: Etanercept<br/><b>Sponsor</b>: Wyeth<br/><b>Recruiting</b> - verified July 2009
A Study Comparing CRx-102 Plus Disease-Modifying Anti-Rheumatic Drug (DMARD) Therapy to Placebo Plus DMARD Therapy in Rheumatoid Arthritis
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Interventions</b>: Other: CRx-102 plus DMARD therapy; Other: Placebo plus DMARD therapy<br/><b>Sponsor</b>: CombinatoRx<br/><b>Completed</b> - verified September 2008
Effects of Tranilast on Pharmacokinetics of Methotrexate (MTX) in Patients With Rheumatoid Arthritis (RA)
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Interventions</b>: Drug: Tranilast; Drug: Placebo comparator<br/><b>Sponsors</b>: Imperial College London; Nuon Therapeutics, Inc.<br/><b>Withdrawn</b> - verified July 2009
RESTART C0168Z05 Rheumatoid Arthritis Study
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: Biological: Infliximab<br/><b>Sponsors</b>: Centocor Ortho Biotech Services, L.L.C.; Schering-Plough<br/><b>Completed</b> - verified July 2010
Humira in Rheumatoid Arthritis - Do Bone Erosions Heal?
<b>Conditions</b>: Rheumatoid Arthritis; Arthritis; Joint Diseases<br/><b>Intervention</b>: Drug: Adalimumab (Humira)<br/><b>Sponsors</b>: Hvidovre University Hospital; Abbott<br/><b>Completed</b> - verified June 2008
Rheumatoid Arthritis (RA) Moderate to Low Disease Activity Study
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Interventions</b>: Drug: Certolizumab pegol; Other: Placebo<br/><b>Sponsor</b>: UCB, Inc.<br/><b>Active, not recruiting</b> - verified June 2010
Study Evaluating Single Doses of SBI-087 in Subjects With Rheumatoid Arthritis
<b>Condition</b>: Rheumatoid Arthritis<br/><b>Intervention</b>: Drug: SBI-087<br/><b>Sponsors</b>: Wyeth; Trubion Pharmaceuticals<br/><b>Active, not recruiting</b> - verified July 2009
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